---
title: Improve Acrylamide Analysis with a Long-Lasting LC Column and a Cost-Effective Internal Standard
description: Acrylamide can form in food when sugars and the amino acid asparagine react during high-heat cooking processes like frying, roasting, grilling, or baking.
image: https://news.mercedesscientific.com/hubfs/RestekAcrylamide.png
---

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# Improve Acrylamide Analysis with a Long-Lasting LC Column and a Cost-Effective Internal Standard

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## Improve Acrylamide Analysis with a Long-Lasting LC Column and a Cost-Effective Internal Standard

[Mercedes Scientific](https://news.mercedesscientific.com/en/blog/author/mercedes-scientific)

 Nov 22, 2024 4:40:09 PM

Acrylamide can form in food when sugars and the amino acid asparagine react during high-heat cooking processes like frying, roasting, grilling, or baking. Acrylamide is classified as a very hazardous chemical, and large quantities of it have been shown to cause cancer in laboratory animals (although no direct link between dietary exposure and increased incidence of cancer in humans has been proven to date). LC-MS/MS is the current analytical technique of choice for food samples.

Restek Allure Acrylamide guard and analytical columns were developed to withstand 100% aqueous mobile phases, and deliver the same robust performance injection to injection, and also column to column. Faster overall acrylamide analysis can be achieved using Allure Acrylamide columns because they ensure sufficient retention of acrylamide, while allowing matrix compounds to be flushed out more efficiently and effectively. Pairing Allure analytical columns and guard cartridges with a deuterated internal standard allows labs to increase productivity and profitability by analyzing more samples, in less time, with fewer columns.

PRODUCT DETAILS:  
Acrylamide  
Item# RTK 30494  
Description: Acrylamide (79-06-1), 1,000μg/mL in methanol, 1mL/ampule (Order by the Each)

Acrylamide-d3  
Item# RTK 30153  
Description: Acrylamide-d3 (122775-19-3), 500 μg/mL in acetonitrile, 5 mL/ampule (Order by the Each) Deuterium-labeled acrylamide is an excellent and cost-effective isotopically labeled internal standard choice for the analysis of acrylamide in food or environmental samples.

Allure Acrylamide LC Column  
Item# RTK 9167552  
Description: 5 μm Columns, 50 mm, 2.1 mm ID

Allure Acrylamide Guard Cartridges  
Item# RTK 916750212  
Description: 5μm, 10 x 2.1mm (Order 3/pack)

Content for this blog entry provided by Restek, a leading developer and manufacturer of chromatography products.

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